ILOKAASU KäRKKäINEN FUNDAMENTALS EXPLAINED

The final proposed system of RBC vasodilation while in the presence of nitrite would be the reduction of nitrite to NO by Hb. Brooks first studied the nitrite Hb interaction in 1937 which perform was afterwards extended by Doyle in 1981 (Brooks, 1937; Doyle et al., 1981). Nitrite reacts with deoxygenated Hb to type metHb and NO (Brooks, 1937; Doyle